Viagra, also known as sildenafil citrate, is a medication used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, which helps to achieve and maintain an erection. In this article, we’ll explore how Viagra works and the mechanism of action behind its effectiveness.

How Viagra Works

Erections are the result of a complex interplay of physical and psychological factors. When a man is sexually stimulated, the nerves in his penis release a chemical called nitric oxide. This chemical triggers the release of another chemical called cyclic guanosine monophosphate (cGMP), which causes the blood vessels in the penis to dilate (widen). This allows blood to flow into the penis and causes it to become erect.

In men with ED, the production of cGMP is disrupted, making it difficult to achieve or maintain an erection. Viagra works by increasing the levels of cGMP in the penis, which helps to improve blood flow and allows for a firm erection.

Mechanism of Action

비아그라 구매 works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). This enzyme is responsible for breaking down cGMP in the penis, which can lead to a decrease in blood flow and difficulty achieving an erection.

By inhibiting PDE5, Viagra helps to increase the levels of cGMP in the penis, leading to improved blood flow and a stronger erection. This effect is selective to the penis, meaning that Viagra does not have a significant impact on blood flow in other parts of the body.

Viagra is rapidly absorbed into the bloodstream after oral administration, with peak plasma concentrations reached within 30 to 120 minutes. The drug is metabolized in the liver and excreted in the feces and urine.

Dosage and Administration

Viagra is available in tablet form, with dosages ranging from 25mg to 100mg. The recommended starting dose is 50mg, taken approximately one hour before sexual activity. The dose may be adjusted based on individual response and tolerability.

It is important to note that Viagra should not be taken more than once per day, and should not be taken with certain medications or substances, such as nitrates or alpha-blockers. It is also important to avoid consuming large amounts of alcohol while taking Viagra, as this can increase the risk of side effects.

Side Effects and Precautions

Viagra is generally considered safe and well-tolerated, but like all medications, it can cause side effects. The most common side effects of Viagra include headache, facial flushing, indigestion, and nasal congestion. These side effects are typically mild and go away within a few hours.

Less common but more serious side effects of Viagra include sudden vision or hearing loss, chest pain, and priapism (a prolonged and painful erection). If any of these side effects occur, it is important to seek medical attention immediately.

Viagra should not be taken by men who are taking nitrates for chest pain or alpha-blockers for high blood pressure, as this can cause a dangerous drop in blood pressure. It is also important to inform your doctor of any other medications you are taking before starting Viagra.

Conclusion

Viagra is a safe and effective treatment for ED that works by increasing blood flow to the penis through the inhibition of PDE5. By improving blood flow and increasing the levels of cGMP in the penis, Viagra can help men achieve and maintain an erection. It is important to follow dosing instructions and precautions when taking Viagra to ensure safety and effectiveness.